Long-term Effects of Flexible Visitation in the ICU on Patients’ Mental Health
Flexible ICU visitation, compared to the restrictive visitation, was associated with a significant reduction in the 1-year prevalence of post-traumatic stress symptoms in family members. A total of 519 family members were... read more
ECLS in Cardiogenic Shock Complicating Acute Myocardial Infarction: Benefit and Harm
Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group. Recently, frequentist analysis showed... read more
ICU Cardiac Arrest Among Very Elderly Critically Ill Patients
The occurrence of ICU-CA in critically ill patients with advanced age (≥ 90 years) is relatively rare. The observed mortality in the ICU and hospital was exceedingly high. Notably, providing cardiopulmonary resuscitation... read more
Evidence-Based Critical Care: A Case Study Approach
This book provides learners with a unique opportunity by virtue of the format outlined above. Each case presentation has a case vignette, which leads up to an important clinical question, and is followed by additional discussion... read more
Optimal Antibiotic Treatment Duration of Upper and Lower Respiratory Tract Infections
The available evidence for non-ICU community-acquired pneumonia (CAP) and chronic obstructive pulmonary disease (AECOPD) supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts... read more
Platelet Transfusions: Ten Things ICU Specialists Need to Know
Thrombocytopenia is common in critically ill patients and is associated with higher bleeding risk and worse outcomes. Platelet transfusions are frequently used to prevent or treat bleeding, though often with uncertain... read more
Corticosteroid Treatment and Survival in Critically Ill COVID-19 Patients
Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid... read more
Critical Care Nephrology and Renal Replacement Therapy in Children
Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more
Oxygen Therapy in Acute Hypoxemic Respiratory Failure
Although largely used, the place of oxygen therapy and its devices in patients with acute hypoxemic respiratory failure (ARF) deserves to be clarified. The French Intensive Care Society (Société de Réanimation de Langue... read more
Conservative or Liberal Oxygen Targets in Patients on VA-ECMO
In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more
Long-term Outcomes in Nutrition Trials
Survivors of critical illness frequently suffer from physical, cognitive and mental disorders after hospital discharge, leading to increased disabilities, poor quality of life, and worse long-term outcomes. Therefore,... read more
Predictive Biomarkers of Mortality in ICU Patients with Severe COVID-19
This study shows changes in hematological, biochemical, and inflammatory parameters in COVID-19 non-surviving patients. Lymphopenia, neutrophilia, and thrombocytopenia, as well as increased levels of CRP, AST, creatinine,... read more
Nitric Oxide Inhibitors Changes and Mortality in Critically Ill Patients
Increasing asymmetric dimethylarginine (ADMA) concentrations on days 1-3 are inversely associated with mortality, however not with the same strength as high ADMA or SDMA concentrations at admission. We suggest that admission... read more
Comorbid Burden at ICU Admission in COVID-19 vs. Sepsis and ARDS
The burden of age and comorbidity is more prominent in ICU-admission for sepsis and acute respiratory distress syndrome (ARDS) than for COVID-19. This is likely to be caused by a combination of COVID-19 affecting the relatively... read more
Low-Frequency Ventilation May Facilitate Weaning in ARDS Treated with ECMO
Low-frequency ventilation is comparable to conventional protective ventilation in patients with ARDS who have been treated with ECMO. However, low-frequency ventilation may support weaning from invasive mechanical ventilation... read more
A prediction model for nonresponsive outcomes in critically ill patients with ARDS undergoing prone position ventilation
In this study, a risk prediction model for nonresponse to prone position ventilation in acute respiratory distress syndrome (ARDS) patients was constructed, which demonstrated good predictive value and clinical utility. Early... read more
Predictors of High-flow Nasal Cannula Failure in COVID-19 Patients
A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of high-flow nasal cannula... read more
Hematological, Inflammatory and Serological Responses Among COVID-19 ICU Patients
A significant association between serum IgG/IgM and ICU admission was observed. Although serum ferritin and LDH can offer information about the extent of inflammation, they are exclusive factors for ICU admission. Significant... read more
Troponin Role in the Diagnosis and Treatment of Acute Pulmonary Embolism
Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences, wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article reviews the various roles of Tn in managing... read more
Influenza and COVID-19 Vaccination Rates Among Children Receiving Long-Term Ventilation
Children with tracheostomy and HV are at high risk of morbidity and mortality from viral ARIs. Among MyTRaCh enrollees, we found significant discrepancy between influenza and COVID-19 vaccination status. Compared with... read more
Early Invasive Strategy Impact on Left Ventricular Function Recovery in Acute Myocardial Infarction Patients
This study underscores the significant benefits of early invasive strategies in improving left ventricular function recovery and reducing adverse outcomes in acute myocardial infarction patients in Pakistan. The findings... read more
Non-invasive vs. Arterial Pressure Monitoring in the Pre-hospital Critical Care Environment
Non-invasive blood pressure measurements are often inaccurate within the pre-hospital critical care setting, particularly in patients with hemodynamic instability which are the group in which the accuracy of vital signs is... read more
