Tag: study
Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients
Compared with surgical cannulation, percutaneous cannulation was independently associated with lower in-hospital mortality and fewer complications. Among 12,592 patients meeting study inclusion, 9,249 (73%) underwent percutaneous... read more
Defining COVID-19 Associated Pulmonary Aspergillosis
The reported prevalence of CAPA in ICU patients with COVID-19 varies greatly by study and may be related to surveillance protocols and inconsistent definitions which may inflate the prevalence of this complication. Further... read more
Predicting Sepsis Severity at First Clinical Presentation
The severity and endotype signatures indicate that distinct immune signatures precede the onset of severe sepsis and lethality, providing a method to triage early sepsis patients. Gene expression signatures were obtained... read more
Resuscitation Using ECPR During In-Hospital Cardiac Arrest Mortality Prediction Score
The RESCUE-IHCA score can be used by clinicians in real time to predict in-hospital death among patients with in-hospital cardiac arrest (IHCA) who are treated with extracorporeal cardiopulmonary resuscitation (ECPR). A... read more
Intravenous Vitamin C Administration to Septic Shock Patients
Our pilot study indicated that intravenous vitamin C did not provide significant decreases in the mean dose or duration of vasopressor infusion. Further research that takes into account the potential impact of intervention... read more
ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models
Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies... read more
Equipotent Ratios for the Most Common Vasopressors
Calculating equipotent doses between vasopressor agents is necessary in clinical practice and research pertaining to the management of shock. This scoping review summarizes conversion ratios between vasopressors and provides... read more
Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions
Weaning protocols for discontinuation of invasive mechanical ventilation often mandate resolution of shock. Whether extubation while receiving vasopressors is associated with harm is uncertain. To examine whether extubation... read more
COVID-19 Vaccine: Safety and Efficacy
Two doses of SCB-2019 vaccine plus CpG and alum provides notable protection against the entire severity spectrum of COVID-19 caused by circulating SAR-CoV-2 viruses, including the predominating delta variant. This ongoing... read more
Assessment of Patiromer Monotherapy for Hyperkalemia in an Acute Care Setting
In this cohort study of patients with acute, non–life-threatening hyperkalemia, a single dose of patiromer was associated with a significant decrease in serum potassium levels and a low incidence of hypokalemia. These... read more
COVID-19 Mortality Prediction Model
While there have been extensive analyses characterizing cellular and humoral responses across the severity spectrum in COVID-19, predictors of outcomes within severe COVID-19 remain to be comprehensively elucidated. Recently,... read more
Ketamine vs. Nonketamine Regimens for Analgosedation in the ICU
Results suggest ketamine as an adjunct analgosedative has the potential to reduce opioid exposure in postoperative and MV patients in the ICU. More RCTs are required before recommending routine use of ketamine in select populations. A... read more
ERC-ESICM Guidelines on Temperature Control After Cardiac Arrest in Adults
The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying... read more
Experiences of ICU Nurses with an Innovative Digital Diary Intervention
ICU nurses reported that the Post-ICU diary had added value for patients and their relatives. However, in the beginning they also experienced barriers such as lack of time, insufficient integration with their own work processes,... read more
Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions
Critically ill COVID-19 patients have highly complex medical needs during transport. Critical care transfer of COVID-19-positive patients by civilian HEMS services, including air transfer, can be achieved safely with specific... read more
Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score
The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S) is an automated, physiologic measure of delirium severity that predicts clinical outcomes with a level of performance comparable to conventional... read more
Peri-arrest Bolus Epinephrine Practices Amongst Pediatric Resuscitation Experts
In this multinational survey of pediatric resuscitation experts, endorsement of peri-arrest bolus epinephrine use was nearly universal, though a few clinicians cited lack of evidence to support this practice. There was... read more
Bivalirudin vs. Heparin for Maintenance Systemic Anticoagulation During ECMO
When compared with heparin-based systemic anticoagulation, bivalirudin demonstrated feasibility and safety as established by the absence of increases in identifiable adverse outcomes while manifesting substantial improvements... read more
